Rare Histological Variants of Mesothelioma: A Guide to Identification and Diagnosis

Rare Histological Variants of Mesothelioma: A Guide to Identification and Diagnosis Mesothelioma is notoriously diverse in its presentation, making diagnosis a challenging puzzle for pathologists. While the epithelioid, sarcomatoid, and biphasic subtypes are well-documented, there are several rare histological variants that can easily be misdiagnosed. These uncommon variants can mimic other malignancies, leading to delayed or incorrect treatment. This article explores the rare subtypes of mesothelioma, their diagnostic pitfalls, and how to differentiate them from other conditions.